Clue : A rare, benign tumor of the adrenal medulla that causes excessive secretion of catecholamines leading to severe hypertension, headaches, palpitations, and intense sweating.

Clue : A tumor outside the pituitary gland that produces excessive hormone causing high cortisol levels, severe hypercortisolism, skin hyperpigmentation, high blood pressure, and muscle weakness.

Clue : A genetic disorder associated with decreased reaction of body tissues to thyroid hormones.

Clue : An extremely rare, autosomal recessive disorder characterized by dark, thick skin, growth retardation, and dysmorphic facial features.

Clue : A group of inherited genetic disorders that cause endocrine tumors. Common symptoms include high calcium levels, neck pain, or hormone imbalances.

Clue : A highly aggressive central nervous system tumor that often presents with headache, vomiting, seizures, ataxia, and cranial nerve palsies.

Clue : A genetic, neuromuscular disorder that causes progressive degeneration resulting in muscle weakness, atrophy, and difficulty with movement, swallowing, and breathing.

Clue : An inherited neurodegenerative disorder leading to DNA repair failure. Progressive walking difficulties, balance issues, and dilated blood vessels in eyes/skin are early childhood symptoms.

Clue : A rare, progressive, and chronic inflammatory neurological disease, causing severe, drug-resistant epilepsy, cognitive decline, and progressive hemiparesis primarily in children under 15 years.

Clue : A polio-like neurological condition causing sudden muscle weakness, loss of reflexes, and limb paralysis due to spinal cord gray matter inflammation requiring immediate hospitalization.

Clue : A rare genetic condition combining urinary incontinence, kidney damage, and an inverted facial expression where smiling appears as crying.

Clue : A potentially life-threatening infection involving gas-forming bacteria within the bladder wall, occurring in diabetic, elderly females and presenting with abdominal pain, fever, and dysuria.

Clue : A condition considered one of the most severe birth defects, causing protruding internal organs, a non-fused pelvis, major spinal abnormalities, a shortened colon, and an imperforate anus.

Clue : An uncommon, pouch-like sac that develops along the female urethra, which can cause pelvic pain, frequent urinary tract infections, blood in urine, and incontinence.

Clue : A rare, inherited autosomal recessive disorder where an excess production of oxalate combines with calcium, leading to recurrent kidney stones, nephrocalcinosis, and often progressive renal failure.

Clue : A rare malignancy that develops in the lower uterine segment or cervix several decades after pregnancy and typically presents as abnormal vaginal bleeding.

Clue : An exceptionally rare and aggressive cancer primarily affecting infants and young children, originating in the lungs and pleura, and presenting with cough, shortness of breath, and fever.

Clue : An aggressive soft tissue cancer, typically affecting young adults near joints in the limbs and causing slow-growing, painful, deep-seated masses.

Clue : A rare tumor of the adrenal gland that causes overproduction of adrenaline and noradrenaline, leading to severely high blood pressure, headaches, palpitations, and excessive sweating.

Clue : A unique and aggressive liver tumor that occurs distinctively in young patients without underlying liver disease.